Major Publications
1.Two specific interactions of GATE16 with TRPML3 and RAB33B regulate autophagy. Sci Rep. 2025 (in revision).
2.MCOLN1/TRPML1-MCOLN3/TRPML3 heteromer and its coupling to Ca2+ sensor SYT5 regulates autophagosome-lysosome fusion in a PtdIns4P-dependent manner. Autophagy 2025.
3. Proximal dendritic localization of NALCN channels underlies tonic and burst firing in nigral dopaminergic neurons. J Physiol. 2023 Jan;601(1):171-193.
4. The intracellular Ca2+ channel TRPML3 is a novel PI3P effector that regulates autophagosome biogenesis. PNAS 2022 Oct 25;119(43)
5. TRPC3 and NALCN channels drive pacemaking in substantia nigra dopaminergic neurons. eLife. 2021 Aug 19;10:e70920.
6. N‐benzhydryl quinuclidine compounds are a potent and Src kinase‐independent inhibitor of NALCN channels. Br J Pharmacol. 2020 Aug;177(16):3795-3810.
7. Palmitoylation controls trafficking of the intracellular Ca2+ channel MCOLN3/TRPML3 to regulate autophagy. Autophagy. 2019;15(2):327-340.